Posts from ‘Spinal Cord Injury(SCI)’

Dec
10

An Ohio company, Synapse Biomedical, created a novel device designed to stimulate natural breathing processes in patients suffering from decreased and degenerating respiration due to upper spinal cord injuries. Dr. Michael DiMaio of the University of Texas Southwestern Medical Center told EurekAlert that, “Patients who have high-level spinal-cord injuries are unable to breathe efficiently because the nerve signals no longer function.” The U.S. Food and Drug Administration approved the NeuRx device for medical use in 2008.

synaps biomedical logo

The device, called the NeuRx diaphragm pacing system, seeks to make many improvements upon older respiratory aid models. Older models consisted of electrodes inserted directly on the phrenic nerve by way of incisions through the neck and chest. The phrenic nerve sends impulses from the brain to the diaphragm by way of the spinal cord, causing the large muscle to expand and contract properly, making the lungs inhale and exhale in a relatively natural fashion.

Other common treatments for spinal cord injury-based respiratory dysfunctions included the use of external mechanical ventilators that work by way of a tube inserted through the front of the throat, which has potential to interfere with speech.

The NeuRx device creators hope to revolutionize the respiratory-aid process with their new device, which works through 4 electrodes implanted into the diaphragm by way of incisions through the front of the lower abdomen. Dr. DiMaio also said of the NeuRx, “[It] has some advantages over traditional ventilators,” … “Patients have more mobility because they don’t have an external ventilator to carry around, and the surgery to implant the device is less invasive than previous treatments.”

The earlier nerve-stimulating electrodes had potential to scar and/or fatigue the phrenic nerve, whereas the NeuRx device works directly on the diaphragm with more diffuse electrical stimulus. The NeuRx also aids spinal cord injury patients to retain their natural speech, since the device does not involve incisions or tubes in the throat.

Other reported benefits of the NeuRx are: decreased incidence of infection, more natural breathing patterns, more mobility, less chance of scarring after surgery, and less chance of infection due to weakened respiratory ability.

Surgeons at the University of Texas Southwestern Medical Center are ready and equipped to begin implanting the device into eligible patients. The hospital is one of 25 total hospitals in the U.S. who are ready to implant the NeuRx in spinal cord injury and other respiratory-impaired patients. Hopefully the NeuRx diaphragm pacing system will provide relief and benefit to spinal cord injury patients in the near future.

References:

Morales, Katherine. (November 25, 2009). “New device implanted by surgeons help paralyzed patients breathe easier.” Retrieved December 9, 2009 from the EurekAlert website: http://www.eurekalert.org/pub_releases/2009-11/usmc-ndi112509.php

Dec
07

Military medical officials have expressed concern over an increase in spinal injuries among U.S. troops coming home from Afghanistan. Afghan insurgents have responded to the increased presence of heavily armored U.S. vehicles with larger and more powerful roadside explosives.

Spinal Cord Injury Iraq

Roadside bombs have become the top killer of U.S. troops in Iraq and Afghanistan. Not only do the roadside bombs lead to crushed spines and other spinal injuries, they also result in traumatic brain injuries when soldiers are exposed to blasts, even with no impact to the head.

A USA Today story reported that the recent increase in spinal injuries occurred among soldiers in Afghanistan and not Iraq. The increase in spinal cord injuries among troops has arisen due to increased potency in roadside bombs used by insurgents. The U.S. Military issued 3500 Mine Resistant Ambush Protected (MRAP) vehicles as an attempt to deal with the roadside bombings. Unfortunately, Afghanistan insurgents responded with stronger and larger bombs.

Some of the 3500 MRAP vehicles deployed in Afghanistan have been lifted a few feet off the ground by roadside bomb explosions. Even though the MRAP vehicle may remain intact, some soldiers have suffered serious spinal cord injuries in the explosions. The MRAP vehicles cost about $1.4 million.

Medical professionals and Army engineers are comparing data to explore possible alterations and improvements to the MRAP vehicle design to make it safer for soldiers who are exposed to increasing roadside bomb possibilities. The MRAP vehicles, which cost about $1.4 million to make, have a hull designed in a V-shape, which helps to deflect the force of explosions away from the center of the vehicle, the USA Today article reported.

Since there are very few paved roads in Afghanistan, rebels can easily bury roadside explosives in the dirt roads, undetectable to soldiers driving along the roads at high speeds. Although the military has recently send over newer and lighter MRAP vehicles with better seating and harnesses, more improvements are still in the works to ensure the vehicles are safe for combat.

Doctors are matching up data on injuries with the victims’ positions in the vehicles at the time of the explosion and the vehicle type in which the accident occurred. Their hope is that engineers will be able to use the data to design more explosion-proof MRAP vehicles and to prevent any further incidence of spinal cord injuries if possible. USA Today reported that a doctor in Kandahar is currently at work designing a shock-absorbing seat that would provide a better guard against spinal cord injuries.

References:

  • Zoroya, Gregg. (November 5, 2009). “Spinal Injuries Up Among Troops.” Retrieved December 6, 2009 from the USA Today website: http://www.usatoday.com/NEWS/usaedition/2009-11-04-1Aied04_ST_U.htm?csp=34
Jul
20

Doctors from the University of Washington in Seattle recently reviewed recovery and follow up data on 342 patients treated for spinal cord injury with halo vest immobilization (HVI). They found that although complications were relatively high, as many as 35 percent of patients experienced difficulties such as pneumonia with the HVI, the treatment proved effective in up to 85 percent of cases.

The complications arose due to pin site infections and instability issues. The doctors also found that the use of HVI in cervical spine injuries can replace the need for surgery in many cases.

The medical team who reviewed the cases concluded that the use of the HVI to treat spinal injuries remains highly effective, in spite of the challenges presented to both patients and their caregivers.

Halo vests, also called halo rings or halo crowns, are used to stabilize the cervical spine following fracture or dislocation of the spine.

Image from here.

Jul
09

In the last few months there has become a crisis in the health care industry. Watch our video now.

Jul
03

Brain and spinal cord injuries are two common results of automobile accidents.  A large number of lawsuits have been filed against General Motors by persons suffering from brain and spinal cord injuries sustained in accidents involving defective GM vehicles or parts, and many of those cases are currently pending.  On June 1, 2009, GM filed for protection from creditors in the Bankruptcy Court for the Southern District of New York, resulting in all pending lawsuits being stayed until the bankruptcy is finalized.  The case was assigned to Judge Robert E. Gerber who is holding hearings on GM’s proposed reorganization at the time of this post.

alyssa

One of the issues Judge Gerber is expected to rule on this week is whether persons injured by defective GM products will retain their rights to sue or continue lawsuits pending against GM.  There are three categories of injured people whose rights will be affected by the Court’s rulings.  The first are people who had filed lawsuits against GM and received judgments prior to the bankruptcy, but had not yet been paid.  These people are considered unsecured creditors of GM.  The second category are those who were injured by GM products and filed lawsuits that were not resolved before the bankruptcy, so their claims are pending subject to the stay.  The final group, are those who will be injured in the future by GM products sold before bankruptcy.   Under pressure from consumer groups and Attorney’s General from more than ten states, , GM agreed in negotiations leading up to this week’s hearings to allow people injured by GM products in the future to retain their rights to sue.  GM has not, however, capitulated on recognizing pending claims and judgments.

An example of the types of claims that would be extinguished if the court approves GM’s proposed plan is the claims of four year old Alyssa Perrino.  Alyssa was a healthy, intelligent  little girl who sustained catastrophic brain injuries requiring removal of a large portion of her skull when a weak seat in the GM vehicle in which she was riding failed rearward and struck her head.  At the time of the accident, Alyssa was properly strapped into her car seat in the rear of the vehicle.  Prior to the accident, Alyssa spoke three languages, but as a result of her brain injuries, she is now only able to speak ten to fifteen words.  Her mobility is severely limited.  Alyssa was lucky to survive the accident, but her life and the life of the Perrino family has been forever changed.  While the Perrino family’s lawsuit against GM was resolved prior to GM’s bankruptcy, it is typical of cases in which defective vehicles caused irreversible brain and spinal cord injuries.

The bankruptcy plan proposed by GM would transfer automotive brands Chevrolet, Cadillac, Buick and GMC to a new company called Vehicle Acquisition Holdings LLC (Newco).  Under the plan, the United States Government would own 60 percent of Newco, the Canadian government would get 12.5 percent, the United Auto Workers Union, 17.5 percent and unsecured creditors, 10 percent.  Existing GM shareholders are not expected to receive any interest in Newco.  Technically, People whose lawsuits the bankruptcy court does not extinguish will proceed against Newco.  Those lawsuits that do not survive the bankruptcy can continue against the “old GM”, but the old GM is not expected to have assets to pay claims even it the lawsuits were successful.

While the proposed reorganization plan submitted by General Motors, would extinguish claims for injuries like Alyssa Perrino’s if they were pending at the time the bankruptcy was filed, ironically,  GM has agreed that the new owner of GM would assume GM’s liability for warranty claims.   Thus, approval of the plan would lead to the illogical result that if a GM part fails under warranty, the new GM would be liable for the repair, but if the same part killed or injured a person prior to the bankruptcy, the new GM would have no liability at all.

On June 19, 2009, the deadline for filing objections to the proposed GM sale, consumer groups, unions and creditors filed objections to the GM bailout.  Philadelphia attorney Barry Bessler is represented a number of consumer groups in the Chrysler bankruptcy and is representing them in the GM proceedings, as well.  During the Chrysler proceedings, Chrysler successfully washed its hands of all past and future product liability claims involving Chrysler products sold prior to the bankruptcy.  Bressler had argued that the GM case is distinguishable from the Chrysler case in terms of the proper way to treat product liability claimants.  Bressler was quoted in Law.Com as saying “[i]n GM, there is no third-party buyer. Hopefully, that means there’s a stronger case [for successor liability].”  Attorneys for people with pending asbestos products liability lawsuits against GM, have filed objections to the proposed plan, as well.

In addition to consumer groups, attorneys general from at least eleven states filed objections to the “no successor liability” provisions of the bankruptcy plan proposed by GM.  Attorneys general from Connecticut, Kentucky, Maryland, Minnesota, Missouri, Nebraska, North Dakota, Montana, Ohio, West Virginia and Vermont filed objections arguing that GM’s plan to extinguish liabilities for injuries cased by safety defects would take key legal rights away from victims.  Attorney General Richard Blumenthal of Connecticut referred to GM’s proposal as “very unfair and unwise “.   In an interview, Blumenthal stated “[s]o much is at stake. We have fought repeatedly for repair or recall of vehicles and parts that are defective so that people can be spared injury, and there are far-reaching ramifications of failing to apply accountability to the New GM.”

Attorneys general from a number of states also filed objections to GM’s proposed plan due to the impact it would have on GM dealers in their states.  In his statement regarding Montana’s objections to the GM proposal, Montana’s Attorney General Steve Bullock said that GM is attempting to circumvent state laws designed to protect auto dealers. According to Bullock, GM has insisted that current GM dealers sign new dealership agreements that force these dealers to waive state laws that were enacted to protect them.  Bullock further stated that, if his state lost dealerships, some consumers in rural areas would have to drive hundreds of miles just to get their cars or trucks serviced.gm_logo_285

In addition to objections on behalf of consumers and dealers, objections to the GM restructuring were also filed by various bondholders who argued that they were treated unfairly vis a vis other creditors.  Finally, the Steelworkers Union filed objections on behalf of retired steelworkers and engineers who said the plan would leave GM without funds to pay health benefits to union-represented retirees and their families. In their objections, the Steelworkers and Engineers said that “GM has been not only unfair, but cruel” in its treatment of the steelworkers and engineers, and that GM was attempting to renege on a deal to create a health care trust for current workers and to protect the health and life insurance benefits of retirees.

A multi-day hearing on GM’s proposed sale began June 30, 2009 .   At the time this article was posted, proceedings were ongoing and Judge Gerber had not ruled on the objections of injured consumers.  Persons interested in following the proceedings in near real time can do so at http://dealbook.blogs.nytimes.com.

The outcome of the negotiations and court proceedings will affect many people who stand to lose jobs, benefits or investments, but none will be more profoundly affected than persons who have suffered catastrophic injuries such as brain and spinal cord injuries caused by defective GM products. With many millions of GM vehicles on U.S. roads, it is impossible to estimate the number of people who will be injured, and lack the resources to obtain essential medical and other services.   Given that many of these people will become medical wards of the States, U.S. taxpayers will continue bailing out and GM and Chrysler long after the astounding infusion of public funds during the current bankruptcy proceedings has been forgotten.

Jun
30

spinalcordinjuryXenoPort, Inc. announced today that they have obtained positive results from their preliminary phase two trial of arbaclofen placarbil (XP19986) for the treatment of spasticity due to a spinal cord injury (SCI).

In today’s press release, XenoPort’s chief medical officer David A. Stamler said that “currently available medications for treating spasticity are often limited by their short duration of action and significant central nervous system side effects. The efficacy and tolerability of AP that were observed in this trial was encouraging, and we believe that AP offers the potential to address important medical needs for SCI patients.”

XenoPort is a biopharmaceutical company that is focused on the development of products that use the body’s “natural transport mechanisms” to improve existing drugs.

XP19986 showed no compelling negative side effects and demonstrated “significant improvements” in comparison with a placebo. It’s “designed to engage natural nutrient transport mechanisms found on intestinal cell membranes, thereby gaining efficient entrance into the bloodstream”, and XenoPort states that it could allow for just one or two needed doses in their future medial trials.

Muscle spasticity can cause many different conditions from an inability to walk to difficulty speaking due to stiffened muscles. If this drug withstands further trials, it may be able to benefit those who are suffering from spasticity caused by a spinal cord injury.

Image from here.

Apr
29

Up until this month, the general consensus estimated the amount at 250,000 and about four million, respectively. Large numbers indeed, but according to a study just released by the Christopher & Dana Reeve Foundation, they fall far short of reality.

Add 40% to the number of those living with paralysis and multiply four million spinal cord injuries by five and you will have a better idea of the actual numbers: 1.275 million spinal cord injuries and 5.6 million who live with some kind of paralysis.

The study (that surveyed more than 33,000 households) was simplified by the president and CEO of the Reeve Foundation to mean “one in 50 Americans is living with some form of paralysis, whether caused by disease, spinal cord injury or neurological damage…someone you know is living with paralysis – a family member, a friend or a work colleague”.

Some key findings:

  • Paralysis and spinal cord injuries are a great deal more widespread than previously assumed.
  • Stroke, followed by spinal cord injuries are the top causes of paralysis.
  • “Household income for those with paralysis is heavily skewed towards lower-income brackets and is significantly lower than household income for the country as a whole. Roughly 25 percent of households with a person who is paralyzed earn less than $10,000 per year, compared with only seven percent of households in the general population.”

This survey is the first of its kind and the data that it collected will help this population obtain the health care that they need. In response to this study, the Reeve Foundation plans to launch a campaign to change public policy for the better – stay tuned for more details!

Apr
23

Over the last couple of years we have been hearing of the push to digitize health records, in hopes of streamlining a patients data for easy access across medical facilities. Yesterday the Mayo clinic announced a partnership with Microsoft’s HealthVault to launch the Mayo Clinic Health Manager, a tool that gives people the ability to store their medical records online as well as sign up for alerts and reminders. This is only the latest in a procession of new online storage services being offered to interested patients.

Using these services you can import your health records from your doctors, hospitals, labs, prescription drug plans, and other healthcare providers by typing them in yourself or uploading data directly from devices such as blood-pressure monitors. Now with just a couple clicks of your mouse, you can view your entire medical history – what medications you have taken, which ones you are currently on, adverse reactions, operations, diagnosis, and even childhood diseases. What’s online is up to you and, if he is a participant in the government supported push for electronic records, your doctor.

We aren’t going to advocate for or against the digitizing of your healthcare history, but we do want to make sure you are taking into consideration the potential dangers of such a move. While the convenience of hopping online to find out what date you started a particular medication may make the process of filling out your insurance claim easier, keep in mind that what’s easy access for you is just as easy for someone else. Yes, we are talking about hackers. Those information pirates that keep developing more and more insidious data-mining processes.

What does it matter if some stranger is copying your medical information? What can it hurt besides your feelings of privacy? A lot, actually.It isn’t just insurance claims that are affected by your medical history, your reputation is also potentially at risk.

M. Eric Johnson, director of the Glassmeyer/McNamee Center for Digital Strategies at Dartmouth’s Tuck School of Business, released a paper in which he said he and his fellow researchers “were able to uncover a number of medical records and other files with medical information online, using file-sharing services generally associated with song-swapping, like LimeWire and Kazaa”. He went on to note that many of our records are already in electronic form on computers in small clinics and laboratories whose security can’t begin to match that offered by the larger data storage facilities.

Johnson cites numerous instances of leaked records leading to identity theft, medical insurance fraud, and even financial fraud. Don’t forget, your social security number is more often than not is included in your medical records, and adding that information to identifying data such as your date of birth, address, and full name give thieves everything they need to make a profit from your information.

When you are considering making your records electronic, make sure you choose a company that has multiple safeguards in place. While there are always ways around even the toughest Internet security, the likelihood of keeping your information private greatly increases depending what program provider you go with. Google Health has partnered with Medco, as Microsoft’s HealthVault has teamed up with the Mayo Clinic, giving the resulting storage systems more clout than lesser known companies such as iHealthRecord or myPHR, but before you make a choice, research them well – your private data is on the line!

Image from here.

Apr
15

Amazon’s Kindle e-book reader has a feature that allows users to set it up so that it “reads” their books aloud. A handy application for those with disabilities that limit their reading capabilities, such as paralysis or blindness, this feature has surprisingly gained some heat.

Mar
17

Scientists with DaVinci Biosciences and Hospital Luis Vernaza have developed a way to effectively treat spinal cord injuries (SCI). Researchers found that injecting a patient’s bone marrow-derived stem cells (BMCs) into the spinal column benefited both acute and chronic SCIs. When a spinal cord is injured, there is hemorrhaging which leads to swelling and restricted blood flow. The injected BMCs promote blood vessel growth, which aids in healing.

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